The Rohlin invariant of an oriented closed spin 3-manifold M is defined to be the signature (mod 16) of an oriented compact spin 4-manifold bounded by M. The vanishing of the Rohlin invariant of an amphicheiral integral homology 3-sphere is a consequence of some elementary properties of the Casson invariant. In this talk we give a new and direct proof of this vanishing property. More precisely, we introduce a certain construction of an oriented compact spin 4-manifold X bounded by M+M+(-M) ('+' denotes the disjoint union) such that, if M is amphicheiral then the signature of X vanishes. The idea of this construction was inspired by the definition of the degree one part Z_1(M) of the Kontsevich-Kuperberg-Thurston invariant of M.